Institut de Chimie Moléculaire et des Matériaux d'Orsay

Vincent Gandon

Bât. 420LCM – ICMMO
Université Paris-Sud
15, rue Georges Clémenceau
91405 Orsay Cedex

+33 1 69 15 39 31


Vincent Gandon received his Ph.D. in 2002 from the University of Reims (group of Prof. Jan Szymoniak). After a postdoctoral stay at the University of California, Riverside, in the group of Prof. Guy Bertrand, he joined the faculty of the University Pierre et Marie Curie in Paris in 2003, as Assistant Professor in the laboratory of Prof. Max Malacria.


In 2009, he was appointed full Professor at the Paris-Sud University with a Research Excellence Chair. Since 2017, he is also affiliated to the Laboratory of Molecular Catalysis of the Ecole Polytechnique.


His research interests are the development of homogeneous catalyzed processes for organic chemistry and the study of reaction mechanisms by computational chemistry.


Vincent has received the Jean Normant Prize (2012) and the Jean-Marie Lehn Prize (2017) of the organic chemistry division of the French Chemical Society. He has been a junior member of the Institut Universtitaire de France (IUF) from 2012 to 2017 and a junior distinguished member of the French Chemical Society for the 2014-2019 period. 


Exploring the Limits of π-Acid Catalysis Using Strongly Electrophilic Main Group Metal Complexes: the case of Zinc and Aluminum. J. Tian, Y. Chen, M. Vayer, A. Djurovic, R. Guillot, R. Guermazi, S. Dagorne, C. Bour, V. Gandon, Chemistry – A European Journal, 2020, n/a

Bimolecular vinylation of arenes by vinyl cations. Z. Li, V. Gandon, C. Bour, Chem. Commun., 2020

Formal [8+3]-Annulation between Azaoxyallyl Cations and Tropones. G. Force, A. Pérot, R. Guillot, V. Gandon, D. Leboeuf, Synthesis, 2020, 52, 553-564

Synthesis of Bridged Tetrahydrobenzo[b]azepines and Derivatives through an Aza-Piancatelli Cyclization/Michael Addition Sequence. S. Wang, R. Guillot, J.-F. Carpentier, Y. Sarazin, C. Bour, V. Gandon, D. Lebœuf, Angewandte Chemie, 2020, 132, 1150-1154

Enantioselective Total Synthesis of Cymoside through a Bioinspired Oxidative Cyclization of a Strictosidine Derivative. Y. Dou, C. Kouklovsky, V. Gandon, G. Vincent, Angew. Chem. Int. Ed., 2020, 59, 1527-1531

Synthesis of Bridged Tetrahydrobenzo[b]azepines and Derivatives through an Aza-Piancatelli Cyclization/Michael Addition Sequence. S. Wang, R. Guillot, J.-F. Carpentier, Y. Sarazin, C. Bour, V. Gandon, D. Leboeuf, Angewandte Chemie International Edition, 2019, 59, 1134-1138

Synthesis of 2-substituted indoles through cyclization and demethylation of 2-alkynyldimethylanilines by ethanol. G. Zhao, C. Roudaut, V. Gandon, M. Alami, O. Provot, Green Chemistry, 2019, 21, 4204-4210

Gold(I)-Catalyzed Synthesis of Furopyrans: Insight into Hetero-Diels-Alder Reactions. R. Pertschi, P. Wagner, N. Ghosh, V. Gandon, G. Blond, Organic Letters, 2019, 21, 6084-6088

Activating Pyrimidines by Pre-distortion for the General Synthesis of 7-Aza-indazoles from 2-Hydrazonylpyrimidines via Intramolecular Diels-Alder Reactions. V. Le Fouler, Y. Chen, V. Gandon, V. Bizet, C. Salome, T. Fessard, F. Liu, K. N. Houk, N. Blanchard, Journal of the American Chemical Society, 2019, 141, 15901-15909

Calcium(II)- and Triflimide-Catalyzed Intramolecular Hydroacyloxylation of Unactivated Alkenes in Hexafluoroisopropanol. C. Qi, S. Yang, V. Gandon, D. Lebœuf, Organic Letters, 2019, 21, 7405-7409

Synthesis of Medium-Sized Carbocycles by Gallium-Catalyzed Tandem Carbonyl-Olefin Metathesis/Transfer Hydrogenation. A. Djurovic, M. Vayer, Z. Li, R. Guillot, J.-P. Baltaze, V. Gandon, C. Bour, Organic Letters, 2019, 21, 8132-8137

Stereoselective Access to (E)-1,3-Enynes through Pd/Cu-Catalyzed Alkyne Hydrocarbation of Allenes. L. Jeanne-Julien, G. Masson, R. Kouoi, A. Regazzetti, G. Genta-Jouve, V. Gandon, E. Roulland, Organic Letters, 2019, 21, 3136-3141

Energizing listless pyrimidines by pre-distortion for the general synthesis of 7-aza-indazoles from 2-hydrazonylpyrimidines via intramolecular Diels-Alder reactions. V. Le Fouler, Y. Chen, V. Gandon, V. Bizet, C. Salome, T. Fessard, F. Liu, K. N. Houk, N. Blanchard, ChemRxiv, 2019, 1-22

Gold-Catalyzed Regioselective Tetradehydro-Diels-Alder Reaction of Yne-Ynamides: Access to 2,3-Dihydrobenzo[f]indoles. B. Prabagar, S. Dutta, V. Gandon, A. K. Sahoo, Asian Journal of Organic Chemistry, 2019, Ahead of Print

Photooxygenation of 2-propargylfurans: a path to structurally diverse nitrogen-containing 5-membered rings. L. Marin, G. Force, R. Guillot, V. Gandon, E. Schulz, D. Lebœuf, Chem. Commun., 2019, 55, 5443-5446

Alkyne Versus Ynamide Reactivity: RegioselectiveRadical Cyclization of Yne-Ynamides. V. Gandon, S. Dutta, R. K. Mallick, R. Prasad, A. K. Sahoo, Angew. Chem. Int. Ed., 2019, 58, 2289 –2294

Umpolung Reactivity of Ynamides: An Unconventional [1,3]-Sulfonyl and [1,5]-Sulfinyl Migration Cascade. V. Gandon, B. Prabagar, R. K. Mallick, R. Prasad, A. K. Sahoo, Angew. Chem. Int. Ed., 2019, 58, 2365 –2370

Bimetallic gold(I) complexes of photoswitchable phosphines: synthesis and uses in cooperative catalysis. T. Arif, C. Cazorla, N. Bogliotti, N. Saleh, F. Blanchard, V. Gandon, R. Metivier, J. Xie, A. Voituriez, A. Marinetti, Catalysis Science & Technology, 2018, 8, 710-715

Selectivity in the Intermolecular Diels-Alder Reaction of Conjugated Trienes: Experimental and Theoretical Approaches. C. Remeur, S. Desrat, V. Gandon, F. Roussi, European Journal of Organic Chemistry, 2018, 2018, 5869-5877

Iodine-Catalyzed Iso-Nazarov Cyclization of Conjugated Dienals for the Synthesis of 2-Cyclopentenones. L. A. Marsili, J. L. Pergomet, V. Gandon, M. J. Riveira, Organic Letters, 2018, 20, 7298-7303

Empirical Estimation of the Molecular Weight of Gold Complexes in Solution by Pulsed-Field Gradient NMR. G. Hamdoun, C. Bour, V. Gandon, J.-N. Dumez, Organometallics, 2018, 37, 4692-4698

Gold-Catalyzed syn-1,2-Difunctionalization of Ynamides via Nitrile Activation. R. Vanjari, S. Dutta, M. P. Gogoi, V. Gandon, A. K. Sahoo, Organic Letters, 2018, 20, 8077-8081

Synthesis of Cyclopenta[b]piperazinones via an Azaoxyallyl Cation. B. Baldé, G. Force, L. Marin, R. Guillot, E. Schulz, V. Gandon, D. Lebœuf, Org. Lett., 2018, 20, 7405-7409

Gallium-Catalyzed Scriabine Reaction. M. Pareek, C. Bour, V. Gandon, Org. Lett., 2018, 20, 6957-6960

Calcium(II)-Catalyzed Intermolecular Hydroarylation of Deactivated Styrenes in Hexafluoroisopropanol. C. Qi, V. Gandon, D. Lebœuf, Angewandte Chemie International Edition, 2018, 57, 14245-14249

Palladium(II)-Catalyzed Diastereoselective 2,3-Trans C(sp3)-H Arylation of Glycosides. N. Probst, G. Grelier, S. Dahaoui, M. Alami, V. Gandon, S. Messaoudi, ACS Catalysis, 2018, 8, 7781-7786

Spatially encoded diffusion-ordered NMR spectroscopy of reaction mixtures in organic solvents. G. Hamdoun, L. Guduff, C. Van Heijenoort, C. Bour, V. Gandon, J.-N. Dumez, Analyst, 2018, 143, 3458-3464

Synthesis of 3-Substituted 3-Bromo-1-phenylallenes from Alkynylcycloheptatrienes. M. Vayer, R. Guillot, C. Bour, V. Gandon, J. Org. Chem., 2018, 83, 11309–11317

Calcium(II)-Catalyzed Intra- and Intermolecular Hydroamidation of Unactivated Alkenes in Hexafluoroisopropanol Alcohol. C. Qi, F. Hasenmaile, V. Gandon, D. Lebœuf, ACS Catalysis, 2018, 8, 1734-1739

Intermolecular rhodium(II)-catalyzed allylic C(sp3)-H amination of cyclic enamides. R. Rey-Rodriguez, G. Jestin, V. Gandon, G. Grelier, P. Retailleau, B. Darses, P. Dauban, I. Gillaizeau, Advanced Synthesis & Catalysis, 2018, 360, 513-518

Reactions Involving Tryptamines and δ-Allenyl Aldehydes: Competition between Pictet-Spengler Reaction and Cyclization to 1-Aminotetralins. V. Gobe, V. Gandon, X. Guinchard, Advanced Synthesis & Catalysis, 2018, 360, 1280-1288

Iron-Catalyzed Reductive Ethylation of Imines with Ethanol. M. Vayer, S. P. Morcillo, J. Dupont, V. Gandon, C. Bour, Angewandte Chemie, International Edition, 2018, 57, 3228-3232

Dissecting the Gold(I)-Catalyzed Carboaminations of N-Allyl Tetrahydro-β-carbolines to Allenes. V. Gobe, M. Dousset, P. Retailleau, V. Gandon, X. Guinchard, Journal of Organic Chemistry, 2018, 83, 898-912

A diversity-oriented synthesis of cyclopenta[b]pyrroles and related compounds through a calcium(ii)/copper(ii) catalytic sequence. L. Marin, R. Guillot, V. Gandon, E. Schulz, D. Lebœuf, Org. Chem. Front., 2018, 5, 640-647

Catalytic Use of Low-Valent Cationic Gallium(I) Complexes as π-Acids. Z. Li, G. Thiery, M. R. Lichtenthaler, R. Guillot, I. Krossing, V. Gandon, C. Bour, Advanced Synthesis & Catalysis, 2018, Volume360, Issue3, 544-549

Triflic acid as an efficient Brønsted acid promoter for the Umpolung of N-Ac indoles in hydroarylation reactions. R. K. Nandi, A. Perez-Luna, D. Gori, R. Beaud, R. Guillot, C. Kouklovsky, V. Gandon, G. Vincent, Adv. Synth. Catal., 2018, 360, 161–172

Functionalization of Mo132 Keplerate Nanocapsules by Cyclic Carboxylates: L-proline vs Cyclopentanecarboxylate. M. Awada, S. Floquet, M. Haouas, N. Watfa, J. Marrot, C. Roch-Marchal, V. Coeffard, C. Greck, C. Bour, V. Gandon, F. Taulelle, E. Cadot, Current Inorganic Chemistry, 2017, 7, 39-47

Intramolecular Inverse Electron-Demand [4 + 2] Cycloadditions of Ynamides with Pyrimidines: Scope and Density Functional Theory Insights. G. Duret, R. Quinlan, B. Yin, R. E. Martin, P. Bisseret, M. Neuburger, V. Gandon, N. Blanchard, Journal of Organic Chemistry, 2017, 82, 1726-1742

Carbon-Carbon and Carbon-Heteroatom Bond-Forming Transformations Catalyzed by Calcium(II) Triflimide. D. Lebœuf, V. Gandon, Synthesis, 2017, 49, 1500-1508

Substitution of the Participating Group of Glycosyl Donors by a Halogen Atom: Influence on the Rearrangement of Transient Orthoesters Formed during Glycosylation Reactions. A. Joosten, M. Boultadakis-Arapinis, V. Gandon, L. Micouin, T. Lecourt, Journal of Organic Chemistry, 2017, 82, 3291-3297

Calcium(II)-Catalyzed Alkenylation of N-Acyliminiums and Related Ions with Vinylboronic Acids. C. Qi, V. Gandon, D. Lebœuf, Advanced Synthesis & Catalysis, 2017, 359, 2671-2675

Enantioselective gold(I)-catalyzed rearrangement of cyclopropyl-substituted 1,6-enynes into 2-oxocyclobutyl-cyclopentanes. Z. Wu, D. Lebœuf, P. Retailleau, V. Gandon, A. Marinetti, A. Voituriez, Chemical Communications (Cambridge, United Kingdom), 2017, 53, 7026-7029

Intramolecular Pd-Catalyzed Anomeric C(sp3)-H Activation of Glycosyl Carboxamides. N. Probst, G. Grelier, N. Ghermani, V. Gandon, M. Alami, S. Messaoudi, Organic Letters, 2017, 19, 5038-5041

Synthesis of Spiroindolenines via Regioselective Gold(I)-Catalyzed Cyclizations of N-Propargyl Tryptamines. V. Magne, A. Marinetti, V. Gandon, A. Voituriez, X. Guinchard, Advanced Synthesis & Catalysis, 2017, 359, 4036-4042

Asymmetric FeII-Catalyzed Thia-Michael Addition Reaction to α,β-Unsaturated Oxazolidin-2-one Derivatives. S. Lauzon, H. Keipour, V. Gandon, T. Ollevier, Organic Letters, 2017, 19, 6324-6327

One-Pot Assembly of Highly Functionalized Cyclopenta[b]pyrroles via a Calcium(II)- and Copper(II)-Catalyzed Reaction Sequence. L. Marin, V. Gandon, E. Schulz, D. Lebœuf, Advanced Synthesis & Catalysis, 2017, 359, 1157-1163

Revealing the Activity of pi-Acid Catalysts Using a 7-Alkynyl Cycloheptatriene. V. Gandon, M. Vayer, R. Guillot, C. Bour, Chemistry – A European Journal, 2017, Volume 23, Issue 56, 13901–13905

Revealing the Electrophilicity of N-Ac Indoles with FeCl3: a mechanistic study. R. Beaud, R. K. Nandi, A. Perez-Luna, R. Guillot, D. Gori, C. Kouklovsky, N. E. Ghermani, V. Gandon, G. Vincent, Chem. Commun., 2017, 53, 5834 - 5837

Catalytic Activity of Gold(I) Complexes with Hemilabile P,N Ligands. B. Michelet, D. Lebœuf, C. Bour, K. Škoch, F. Horký, P. Štěpnička, V. Gandon, ChemPlusChem, 2017, 82, 442-448

Synthesis and Characterizations of Keplerate Nanocapsules Incorporating L- and D-Tartrate Ligands. M. Awada, S. Floquet, J. Marrot, M. Haouas, S. P. Morcillo, C. Bour, V. Gandon, V. Coeffard, C. Greck, E. Cadot, Journal of Cluster Science, 2017, 1-14

Acid-catalysed intramolecular addition of [small beta]-ketoesters to 1,3-dienes. M. Vayer, W. Fang, R. Guillot, S. Bezzenine-Lafollee, C. Bour, V. Gandon, Org. Biomol. Chem., 2017, 15, 584-588