Institut de Chimie Moléculaire et des Matériaux d'Orsay

Thomas Boddaert

Enseignant-Chercheur
Bât. 420CP3A – ICMMO
Université Paris-Sud
15, rue Georges Clémenceau
91405 Orsay Cedex
FRANCE

thomas.boddaert@u-psud.fr
https://orcid.org/0000-0002-3939-4700

Parcours:

Dr. Thomas Boddaert was born in 1982 in Lille (France). He graduated in 2006 from the Ecole Supérieure de Chimie Organique et Minérale (ESCOM), in the course of which he spent one year trainee at Syngenta in Bracknell (UK). In 2006, he also obtained his M. Sc. degree from Cergy-Pontoise University in the group of Prof. Janick Ardisson and Dr. Ange Pancrazi. He completed his PhD in 2009 at Aix-Marseille University under the supervision of Prof. Jean Rodriguez and Dr. Yoann Coquerel where he worked on the development of new domino/consecutive transformations in the field of organocatalysis (NHCs) and the application on total synthesis. He then joined Prof. Jonathan Clayden at Manchester University as a one year postdoctoral associate where he worked on the conformational control over the screw sense of an achiral helical peptide foldamer. Late 2010, he returned to France for two additional postdoctoral years in the group of Dr. Jacques Maddaluno at Rouen University to study an intramolecular anionic rearrangement for the synthesis of silylated and germylated heterocycles in collaboration with Janssen-Cilag. Since 2012, he works as a “Maître de Conférences” with Prof. David J. Aitken at the Institut de Chimie Moléculaire et des Matériaux d’Orsay (ICMMO) at Paris Sud University. His research interests include methodologies based on photochemical transformations, synthesis of constrained β-amino acids and conformational studies of their oligomers.

 

Publications:

A Selective Deprotection Strategy for the Construction of trans-2-Aminocyclopropanecarboxylic Acid Derived Peptides. T. Boddaert, J. E. Taylor, S. D. Bull, D. J. Aitken, Org. Lett., 2019, 21, 100-103

Formation de liaisons Si-C pour la synthèse d'hétérocycles silylés. M. Durandetti, T. Boddaert, L'Actualité Chimique, 2018, 434, 11-18

Acid-catalyzed synthesis of functionalized arylthio cyclopropane carbaldehydes and ketones. S. Porcu, A. Luridiana, A. Martis, A. Frongia, G. Sarais, D. J. Aitken, T. Boddaert, R. Guillot, F. Secci, Chem. Commun., 2018, 54, 13547-13550

Preparation of cyclobutene acetals and tricyclic oxetanes via photochemical tandem and cascade reactions. J. Buendia, Z. Chang, H. Eijsberg, R. Guillot, A. Frongia, F. Secci, J. Xie, S. Robin, T. Boddaert, D. J. Aitken, Angewandte Chemie International Edition, 2018, 57, 6592-6596

Cooperative 5- and 10-membered ring interactions in the 10-helix folding of oxetin homo-oligomers. S. S. Ragab, A. F. Kassir, R. Guillot, M.-C. Scherrmann, T. Boddaert, D. J. Aitken, Chem. Commun., 2018, 54, 1968-1971

A Photochemical Route to 3- and 4-Hydroxy Derivatives of 2-Aminocyclobutane-1-carboxylic Acid with an all-cis Geometry. Z. Chang, F. Boyaud, R. Guillot, T. Boddaert, D. J. Aitken, Journal of Organic Chemistry, 2018, 83, 527-534

Synthesis of 2,2-bis(pyridin-2-yl amino)cyclobutanols and their conversion into 5-(pyridin-2-ylamino)dihydrofuran-2(3H)-ones. L. Ghisu, N. Melis, F. Secci, P. Caboni, M. Arca, R. Guillot, T. Boddaert, D. J. Aitken, A. Frongia, Org. Biomol. Chem., 2017, 15, 9779-9784

Stereoselective and regioselective pinacol-type rearrangement of a fused bicyclic oxetanol scaffold. N. Melis, A. Luridiana, R. Guillot, F. Secci, A. Frongia, T. Boddaert, D. J. Aitken, European Journal of Organic Chemistry, 2017, 2017, Issue 39, 5896–5902

Synthetic access to all four stereoisomers of oxetin. A. F. Kassir, S. S. Ragab, T. A. M. Nguyen, F. Charnay-Pouget, R. Guillot, M.-C. Scherrmann, T. Boddaert, D. J. Aitken, J. Org. Chem., 2016, 81, 9983-9991

Synthesis of functionalized tryptamines by Bronsted acid catalysed cascade reactions. N. Melis, F. Secci, T. Boddaert, D. J. Aitken, A. Frongia, Chem. Commun., 2015, 51, 15272-15275

Conformational preferences in the β-peptide oligomers of cis-2-amino-1-fluorocyclobutane-1-carboxylic acid. A. Hassoun, C. M. Grison, R. Guillot, T. Boddaert, D. J. Aitken, New J. Chem., 2015, 39, 3270-3279