Institut de Chimie Moléculaire et des Matériaux d'Orsay

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2.11. Complexes modèles de β-lactamases

W. Ghattas


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Current zinc and cobalt metal complexes perform poorly in mimicking the activity of β-lactamases. We identified the best performing complexes and are trying to improve their activity. This is performed by modifying their structure & coordinating atoms by biomiming the active sites of natural β-lactamases.