CP3A ORGANIC SYNTHESIS GROUP
Peptidomimetic Chemistry, Photochemistry, Alternative Processes
Team publications
2024
Light-Initiated Four-Step Domino-Multicomponent Synthesis of Functionalized Alkylidenecyclobutanes. X. Yu, A. Desvals, Z. Chang, V. Orève, D. J. Aitken, T. Boddaert, Organic Letters, 2024, 26, 9915-9919
In Situ Generation of 1-Acetylpyrene as a Visible-Light Photocatalyst for the Thia-Paternò-Büchi Reaction. G. Cormier, C. Allain, T. Boddaert, Angewandte Chemie International Edition, 2024, n/a, e202412602
Rapid Synthesis of anti-1,3-Diamino-4-phenylbutan-2-ol Building Blocks via a Three-Component Oxyhomologation and a Two-Component Reducing System. M. C. Cabua, X. He, F. Secci, S. Deloisy, D. J. Aitken, ChemistryOpen, 2024, e202400279
Substrate-dependent regiodivergence in [3 + 2] annulation reactions of 2-(phenacylethylidene)cyclobutanones with thioureas. S. Barranco, A. Pagnanini, F. Cuccu, P. Caboni, R. Guillot, D. J. Aitken, A. Frongia, Organic & Biomolecular Chemistry, 2024, 22, 8048-8053
Synthesis of cyclobutane-fused oxazolidine-2-thione derivatives. S. Barranco, F. Cuccu, F. Devoto, R. Guillot, P. Caboni, D. J. Aitken, A. Frongia, Tetrahedron Letters, 2024, 139, 155009
High anti Diastereoselectivity in a Tandem Oxyhomologation−Coupling Protocol for the Preparation of Amides and Peptides Incorporating α‑Hydroxy β‑Amino Acids. X. He, R. Guillot, S. Deloisy, D. J. Aitken, Organic Letters, 2024, 26, 2207-2211
Effects of sulfoxide and sulfone sidechain–backbone hydrogen bonding on local conformations in peptide models. D. Liu, S. Robin, E. Gloaguen, V. Brenner, M. Mons, D. J. Aitken, Chemical Communications, 2024, 60, 2074-2077
2023
A New Strategy for the Preparation of 3-Amino-4-hydroxypyrrolidinone-4-acetic Acid, an Unusual γ-Amino Acid found in Microsclerodermins. Y.-P. Liu, D. J. Aitken, V. Declerck, European Journal of Organic Chemistry, 2023, 26, e202300767
Functionalized alkylidenecyclobutanes from a cyclopent-2-enone substrate via a tandem photochemical transformation and an allylic substitution protocol. X. Yu, T. Boddaert, D. J. Aitken, Advanced Synthesis & Catalysis, 2023, 365, 4002-4007
trans-3-Benzyloxycarbonylamino-1-methyl-3-(methylcarbamoyl)azetidine-1-oxide. D. Liu, R. Guillot, S. Robin, D. J. Aitken, Molbank, 2023, 2023, M1726
Length-Dependent Transition from Extended to Folded Shapes in Short Oligomers of an Azetidine-Based α-Amino Acid: The Critical Role of NH···N H-Bonds. D. Liu, J.-X. Bardaud, Z. Imani, S. Robin, E. Gloaguen, V. Brenner, D. J. Aitken, M. Mons, Molecules, 2023, 28, 5048
A Post-Synthetic Modification Strategy for the Preparation of Homooligomers of 3-Amino-1-methylazetidine-3-carboxylic acid. D. Liu, Z. Imani, C. Gourson, R. Guillot, S. Robin, D. J. Aitken, Synlett, 2023, 34, 1787-1790
β-N-Heterocyclic Cyclobutane Carboximides: Synthesis Via a Tandem Base-Catalyzed Amidation/aza-Michael Addition Protocol and Facile Transformations. S. Barranco, F. Cuccu, D. Liu, S. Robin, R. Guillot, F. Secci, V. Brenner, M. Mons, P. Caboni, D. J. Aitken, A. Frongia, European Journal of Organic Chemistry, 2023, 26, e202300183
Non-covalent interactions reveal the protein chain δ conformation in a flexible single-residue model. Z. Imani, V. R. Mundlapati, V. Brenner, E. Gloaguen, K. Le Barbu-Debus, A. Zehnacker-Rentien, S. Robin, D. J. Aitken, M. Mons, Chemical Communications, 2023, 59, 1161-1164
2022
Solvent-Free Synthesis of Quaternary Oxazolidine-2-thione β3-Amino Ester Analogs. F. Soddu, F. Devoto, V. Marras, P. Caboni, F. Secci, D. J. Aitken, A. Frongia, European Journal of Organic Chemistry, 2022, 2022, e202201115
Preparation of Thietane Derivatives through Domino Photochemical Norrish Type II/Thia-Paternò–Büchi Reactions. M. I. Lapuh, G. Cormier, S. Chergui, D. J. Aitken, T. Boddaert, Organic Letters, 2022, 24, 8375-8380
Characterization of Asx Turn Types and Their Connate Relationship with β-Turns. V. D'Mello, G. Goldsztejn, V. R. Mundlapati, V. Brenner, E. Gloaguen, F. Charnay-Pouget, D. J. Aitken, M. Mons, Chemistry - A European Journal, 2022, 28, e202104328
A case study of the MAC (Masked Acyl Cyanide) oxyhomologation of N,N-dibenzyl-L-phenylalaninal with anti diastereoselectivity: preparation of (2S,3S)-allophenylnorstatin esters. X. He, M. Buchotte, R. Guillot, S. Deloisy, D. J. Aitken, Organic & Biomolecular Chemistry, 2022, 20, 1769-1781
2021
Synthesis and Applications of Carbohydrate-Based Organocatalysts. E. Wojaczyńska, F. Steppeler, D. Iwan, M.-C. Scherrmann, A. Marra, Molecules, 2021, 26, 7291
N–H···X interactions stabilize C5 intra-residue hydrogen bonding in heterocyclic α-amino acid derivatives. V. R. Mundlapati, Z. Imani, V. C. D'Mello, V. Brenner, E. Gloaguen, J.-P. Baltaze, S. Robin, M. Mons, D. J. Aitken, Chemical Science, 2021, 12, 14826-14832
Photoactivatable Small-Molecule Inhibitors for Light-Controlled TAM Kinase Activity. J. Le Bescont, L. Mouawad, T. Boddaert, S. Bombard, S. Piguel, ChemPhotoChem, 2021, 5, 989-994
Ion Pair Supramolecular Structure Identified by ATR-FTIR Spectroscopy and Simulations in Explicit Solvent. J. Donon, S. Habka, T. Very, F. Charnay-Pouget, M. Mons, D. J. Aitken, V. Brenner, E. Gloaguen, ChemPhysChem, 2021, 22, 2442-2455
A Brønsted acid catalyzed tandem reaction for the diastereoselective synthesis of cyclobuta-fused tetrahydroquinoline carboxylic esters. V. Marras, P. Caboni, F. Secci, R. Guillot, D. J. Aitken, A. Frongia, Organic & Biomolecular Chemistry, 2021, 19, 8912-8916
Pyrrolidinyl peptide nucleic acids bearing hydroxy-modified cyclobutane building blocks: Synthesis and binding properties. B. Ditmangklo, W. Sittiwong, T. Boddaert, T. Vilaivan, D. J. Aitken, Biopolymers (Peptide Science), 2021, 112, e23459
A theoretical and experimental case study of the hydrogen bonding predilection of S-methylcysteine. V. R. Mundlapati, Z. Imani, G. Goldsztejn, E. Gloaguen, V. Brenner, K. Le Barbu-Debus, A. Zehnacker-Rentien, J.-P. Baltaze, S. Robin, M. Mons, D. J. Aitken, Amino Acids, 2021, 53, 621-633
A short synthesis of both enantiomers of 2-aminobicyclo[3.2.0]heptane-2,7-dicarboxylic acid. F. Charnay-Pouget, M. Le Liepvre, H. Eijsberg, R. Guillot, J. Ollivier, F. Secci, A. Frongia, D. J. Aitken, Tetrahedron Letters, 2021, 68, 152912
Synthesis of Tryptamines through a Novel Brønsted Acid Mediated Tandem Reaction Initiated by α-Iminol Rearrangement of Transient 2-Substituted 2-Hydroxycyclobutylimines. L. Serusi, F. Cuccu, F. Secci, D. J. Aitken, A. Frongia, Synthesis, 2021, 53, 673-681
2020
Formation of tetrahydrothiophenes via a thia-Paternò-Büchi-initiated domino photochemical reaction. A. F. Kassir, R. Guillot, M.-C. Scherrmann, T. Boddaert, D. J. Aitken, Org. Lett., 2020, 22, 8522-8527
Conformation control through concurrent N–H⋯S and N–H⋯O=C hydrogen bonding and hyperconjugation effects. Z. Imani, V. R. Mundlapati, G. Goldsztejn, V. Brenner, E. Gloaguen, R. Guillot, J.-P. Baltaze, K. Le Barbu-Debus, S. Robin, A. Zehnacker, M. Mons, D. J. Aitken, Chem. Sci., 2020, 11, 9191-9197
Synthesis of α‐aminocyclopropyl ketones and 2-substituted benzoimidazoles from 2-hydroxycyclobutanones and aryl amines. L. Serusi, F. Soddu, F. Cuccu, G. Peretti, A. Luridiana, F. Secci, P. Caboni, D. J. Aitken, A. Frongia, Advanced Synthesis and Catalysis, 2020, 362, 4159-4163
Local versus global control of helical folding in β-peptide segments using hydrazino turns. Z. Imani, R. Guillot, V. Declerck, D. J. Aitken, J. Org. Chem., 2020, 85, 6165-6171
Young Career Focus. T. Boddaert, Synform, 2020, 3, A62-A64
2019
Discoveries through organocatalyzed, Brønsted acid catalyzed and non-catalyzed transformations of 2-hydroxycyclobutanone. D. J. Aitken, A. Frongia, F. Secci, Vietnam Journal of Chemistry, 2019, 57, 661-669
Tandem Wittig reaction-ring contraction of cyclobutanes: a simple route to functionalized cyclopropane carbaldehydes. F. Cuccu, L. Serusi, A. Luridiana, F. Secci, P. Caboni, D. J. Aitken, A. Frongia, Org. Lett., 2019, 21, 7755-7758
Eucalyptol: a new solvent for the synthesis of heterocycles containing oxygen, sulfur and nitrogen. J. F. Campos, M.-C. Scherrmann, S. Berteina-Raboin, Green Chemistry, 2019, 21, 1531-1539
Stereocontrolled Preparation of Diversely Trifunctionalized Cyclobutanes. Z. Chang, R. Guillot, T. Boddaert, D. J. Aitken, J. Org. Chem., 2019, 84, 10518-10525
Vibrational circular dichroism as a probe of solid-state organisation of derivatives of cyclic β-amino acids: Cis- and trans-2-aminocyclobutane-1-carboxylic acid. V. Declerck, A. Pérez-Mellor, R. Guillot, D. J. Aitken, M. Mons, A. Zehnacker, Chirality, 2019, 31, 547-560
Synthesis of β-sulfinyl cyclobutane carboxylic amides via a formal α to β sulphoxide migration process. L. Ghisu, N. Melis, L. Serusi, A. Luridiana, F. Soddu, F. Secci, P. Caboni, R. Guillot, D. J. Aitken, A. Frongia, Org. Biomol. Chem., 2019, 17, 6143-6147
Identification of ion pairs in solution by IR spectroscopy: crucial contributions of gas phase data and simulations. S. Habka, T. Very, J. Donon, V. Vaquero-Vara, B. Tardivel, F. Charnay-Pouget, M. Mons, D. J. Aitken, V. Brenner, E. Gloaguen, Phys. Chem. Chem. Phys., 2019, 21, 12798-12805
Reversal of Diastereoselectivity in a Masked Acyl Cyanide (MAC) Reaction: Synthesis of Protected erythro-β-Hydroxyaspartate Derivatives. M. Esgulian, M. Buchotte, R. Guillot, S. Deloisy, D. J. Aitken, Org. Lett., 2019, 21, 2378-2382
Brønsted acid catalysed synthesis of 3-(2-alkoxyethyl)indoles from α‐arylaminocyclobutanones and alcohols. L. Serusi, M. Bonnans, A. Luridiana, F. Secci, P. Caboni, T. Boddaert, D. J. Aitken, A. Frongia, Advanced Synthesis & Catalysis, 2019, 361, 1908-1912
A Selective Deprotection Strategy for the Construction of trans-2-Aminocyclopropanecarboxylic Acid Derived Peptides. T. Boddaert, J. E. Taylor, S. D. Bull, D. J. Aitken, Org. Lett., 2019, 21, 100-103
2018
Formation de liaisons Si-C pour la synthèse d'hétérocycles silylés. M. Durandetti, T. Boddaert, L'Actualité Chimique, 2018, 434, 11-18
Brønsted Acid Mediated Cascade Reaction to Access 3‑(2-Bromoethyl)benzofurans. S. Porcu, S. Demuro, A. Luridiana, A. Cocco, A. Frongia, D. J. Aitken, F. Charnay-Pouget, R. Guillot, G. Sarais, F. Secci, Org. Lett., 2018, 20, 7699-7702
Acid-catalyzed synthesis of functionalized arylthio cyclopropane carbaldehydes and ketones. S. Porcu, A. Luridiana, A. Martis, A. Frongia, G. Sarais, D. J. Aitken, T. Boddaert, R. Guillot, F. Secci, Chem. Commun., 2018, 54, 13547-13550
Fullerene Helical Peptide: Synthesis, Characterization and Formation of Self-Assembled Monolayers on gold surfaces. H. Nasrallah, J. Rabah, V. Bui-Thi-Tuyet, K. Baczko, H. Fensterbank, F. Bourdreux, A.-M. Goncalves, V. Declerck, S. Boujday, V. Humblot, K. Wright, A. Vallée, E. Allard, New J. Chem., 2018, 42, 19423-19432
Strategic C to N Replacement in β-Peptides: Atomic Level Control of Helical Folding. V. Declerck, D. J. Aitken, J. Org. Chem., 2018, 83, 8793-8800
A Greener and Efficient Method for Nucleophilic Aromatic Substitution of Nitrogen-Containing Fused Heterocycles. J. F. Campos, M. Loubidi, M.-C. Scherrmann, S. Berteina-Raboin, Molecules, 2018, 23, 684
Preparation of cyclobutene acetals and tricyclic oxetanes through photochemical tandem and cascade reactions. J. Buendia, Z. Chang, H. Eijsberg, R. Guillot, A. Frongia, F. Secci, J. Xie, S. Robin, T. Boddaert, D. J. Aitken, Angewandte Chemie International Edition, 2018, 57, 6592-6596
Cooperative 5- and 10-membered ring interactions in the 10-helix folding of oxetin homo-oligomers. S. S. Ragab, A. F. Kassir, R. Guillot, M.-C. Scherrmann, T. Boddaert, D. J. Aitken, Chem. Commun., 2018, 54, 1968-1971
A Photochemical Route to 3- and 4-Hydroxy Derivatives of 2-Aminocyclobutane-1-carboxylic Acid with an all-cis Geometry. Z. Chang, F. Boyaud, R. Guillot, T. Boddaert, D. J. Aitken, Journal of Organic Chemistry, 2018, 83, 527-534
2017
Identification of insulin-sensitizing molecules acting by disrupting the interaction between the Insulin Receptor and Grb14. A. Gondoin, C. Hampe, R. Eudes, C. Fayolle, C. Pierre-Eugène, M. Miteva, B. O. Villoutreix, F. Charnay-Pouget, D. J. Aitken, T. Issad, A.-F. Burnol, Scientific Reports, 2017, 7, 16901
Acid-catalyzed reaction of 2-hydroxycyclobutanone with benzylic alcohols. A. Martis, A. Luridiana, A. Frongia, M. Arca, G. Sarais, D. J. Aitken, R. Guillot, F. Secci, Org. Biomol. Chem., 2017, 15, 10053-10063
Synthesis of 2,2-bis(pyridin-2-yl amino)cyclobutanols and their conversion into 5-(pyridin-2-ylamino)dihydrofuran-2(3H)-ones. L. Ghisu, N. Melis, F. Secci, P. Caboni, M. Arca, R. Guillot, T. Boddaert, D. J. Aitken, A. Frongia, Org. Biomol. Chem., 2017, 15, 9779-9784
β-Cyclodextrin-Mediated Enantioselective Photochemical Electrocyclization of 1,3-Dihydro-2H-azepin-2-one. A. T. Mansour, J. Buendia, J. Xie, F. Brisset, S. Robin, D. Naoufal, O. Yazbeck, D. J. Aitken, J. Org. Chem., 2017, 82, 9832-9836
Stereoselective and regioselective pinacol-type rearrangement of a fused bicyclic oxetanol scaffold. N. Melis, A. Luridiana, R. Guillot, F. Secci, A. Frongia, T. Boddaert, D. J. Aitken, European Journal of Organic Chemistry, 2017, 2017, Issue 39, 5896–5902
Conformational effects through hydrogen bonding in a constrained γ-peptide template: from intra-residue 7-membered rings to a gel-forming sheet structure. H. Awada, C. M. Grison, F. Charnay-Pouget, J.-P. Baltaze, F. Brisset, R. Guillot, S. Robin, A. Hachem, N. Jaber, D. Naoufal, O. Yazbeck, D. J. Aitken, J. Org. Chem., 2017, 82, 4819–4828
Studies on cyclization reactions of 3-amino-2,4-dihydroxybutanoic acid derivatives. M. Esgulian, V. Belot, R. Guillot, S. Deloisy, D. J. Aitken, Org. Biomol. Chem., 2017, 15, 1453-1462
2016
The weight of flash chromatography: A tool to predict its mass intensity from thin-layer chromatography. F. Pessel, J. Augé, I. Billault, M.-C. Scherrmann, Beilstein Journal of Organic Chemistry, 2016, 12, 2351–2357
Synthetic access to all four stereoisomers of oxetin. A. F. Kassir, S. S. Ragab, T. A. M. Nguyen, F. Charnay-Pouget, R. Guillot, M.-C. Scherrmann, T. Boddaert, D. J. Aitken, J. Org. Chem., 2016, 81, 9983-9991
Iodine-catalyzed formation of substituted 2-aminobenzothiazole derivatives in PEG400. G. Dumonteil, M.-A. Hiebel, M.-C. Scherrmann, S. Berteina-Raboin, RSC Advances, 2016, 6, 73517-73521
An α-Helix-Mimicking 12,13-Helix: Designed α/β/γ-Foldamers as Selective Inhibitors of Protein–Protein Interactions. C. M. Grison, J. A. Miles, S. Robin, A. J. Wilson, D. J. Aitken, Angewandte Chemie International Edition, 2016, 55, 11096-11100
Total synthesis of triazole-linked C-glycosyl flavonoids in alternative solvents and environmental assessment in terms of reaction, workup and purification. F. Pessel, I. Billault, M.-C. Scherrmann, Green Chem., 2016, 18, 5558-5568
Synthesis and antiproliferative activity of a natural like glycoconjugate polycyclic compound. B. Maggio, M. V. Raimondi, D. Raffa, F. Plescia, M.-C. Scherrmann, N. Prosa, M. Lauricella, A. D’Anneo, G. Daidone, European Journal of Medicinal Chemistry, 2016, 122, 247-256
13-Helix folding of a β/γ-peptide manifold designed from a "minimal-constraint" blueprint. C. M. Grison, S. Robin, D. J. Aitken, Chem. Commun., 2016, 52, 7802-7805
Deracemizing organocatalyzed Michael addition reactions of 2-(arylthio)cyclobutanones with β-nitrostyrenes. A. Luridiana, A. Frongia, D. J. Aitken, R. Guillot, G. Sarais, F. Secci, Org. Biomol. Chem., 2016, 14, 3394-3403
Thermodynamic and Structural Investigation of Synthetic Actinide–Peptide Scaffolds. S. Safi, A. Jeanson, J. Roques, P. L. Solari, F. Charnay-Pouget, C. Den Auwer, G. Creff, D. J. Aitken, E. Simoni, Inorg. Chem., 2016, 55, 877-886
2015
The leguminous species Anthyllis vulneraria as a Zn-hyperaccumulator and eco-Zn catalyst resources. C. M. Grison, M. Mazel, A. Sellini, V. Escande, J. Biton, C. Grison, Environmental Science and Pollution Research, 2015, 22, 5667-5676
Metallophytes for organic synthesis: towards new bio-based selective protection/deprotection procedures. C. M. Grison, A. Velati, V. Escande, C. Grison, Environmental Science and Pollution Research, 2015, 22, 5686-5698
Intrinsic Folding Proclivities in Cyclic β-Peptide Building Blocks: Configuration and Heteroatom Effects Analyzed by Conformer-Selective Spectroscopy and Quantum Chemistry. M. Alauddin, E. Gloaguen, V. Brenner, B. Tardivel, M. Mons, A. Zehnacker-Rentien, V. Declerck, D. J. Aitken, Chemistry – A European Journal, 2015, 21, 16479-16493
Enantioselective Organocatalyzed Desymmetrization of 3-Substituted Cyclobutanones through Michael Addition to Nitroalkenes. F. Capitta, A. Frongia, J. Ollivier, D. J. Aitken, F. Secci, P. P. Piras, R. Guillot, Synlett, 2015, 26, 123-126
Synthesis of functionalized tryptamines by Bronsted acid catalysed cascade reactions. N. Melis, F. Secci, T. Boddaert, D. J. Aitken, A. Frongia, Chem. Commun., 2015, 51, 15272-15275
The discovery of 9/8-ribbons, β/γ-peptides with curved shapes governed by a combined configuration-conformation code. C. M. Grison, S. Robin, D. J. Aitken, Chem. Commun., 2015, 51, 16233-16236
Fine Tuning of β-Peptide Foldamers: a Single Atom Replacement Holds Back the Switch from an 8-Helix to a 12-Helix. A. Altmayer-Henzien, V. Declerck, J. Farjon, D. Merlet, R. Guillot, D. J. Aitken, Angewandte Chemie International Edition, 2015, 54, 10807-10810
Catalytic Enantioselective Synthesis of α-(Benzylamino)cyclobutanones. N. Melis, L. Ghisu, R. Guillot, P. Caboni, F. Secci, D. J. Aitken, A. Frongia, European Journal of Organic Chemistry, 2015, 2015, 4358-4366
Cupreine grafted onto silica as an enantioselective and recyclable catalyst for the 1,4-addition of malonate to trans-β-nitrostyrene. I. Billault, R. Launez, M.-C. Scherrmann, RSC Advances, 2015, 5, 29386-29390
Investigation of the copper(I) catalysed azide-alkyne cycloaddition reactions (CuAAC) in molten PEG2000. I. Billault, F. Pessel, A. Petit, R. Turgis, M.-C. Scherrmann, New J. Chem., 2015, 39, 1986-1995
Pushing the limits of signal resolution to make coupling measurement easier. J. E. H. Pucheta, D. Pitoux, C. M. Grison, S. Robin, D. Merlet, D. J. Aitken, N. Giraud, J. Farjon, Chem Commun, 2015, 51, 7939-7942
Conformational preferences in the β-peptide oligomers of cis-2-amino-1-fluorocyclobutane-1-carboxylic acid. A. Hassoun, C. M. Grison, R. Guillot, T. Boddaert, D. J. Aitken, New J. Chem., 2015, 39, 3270-3279
2014
A simple synthesis of 2-keto-3-deoxy-D-erythro-hexonic acid isopropyl ester, a key sugar for the bacterial population living under metallic stress. C. M. Grison, B.-L. Renard, C. Grison, Bioorganic Chemistry, 2014, 52, 50-55
Direct Spectroscopic Evidence of Hyperconjugation Unveils the Conformational Landscape of Hydrazides. E. Gloaguen, V. Brenner, M. Alauddin, B. Tardivel, M. Mons, A. Zehnacker-Rentien, V. Declerck, D. J. Aitken, Angewandte Chemie International Edition, 2014, 53, 13756-13759
Recent Progress in the Synthetic Assembly of 2-Cyclopentenones. D. J. Aitken, H. Eijsberg, A. Frongia, J. Ollivier, P. P. Piras, Synthesis, 2014, 46, 1-24
Catalytic Enantioselective Synthesis of α-Arylaminocyclobutanones. D. J. Aitken, P. Caboni, H. Eijsberg, A. Frongia, R. Guillot, J. Ollivier, P. P. Piras, F. Secci, Adv. Synth. Catal., 2014, 356, 941-945
Straightforward Synthesis of Various 2,3-Diarylimidazo[1,2-α]pyridines in PEG400 Medium through One-Pot Condensation and C–H Arylation. M.-A. Hiebel, Y. Fall, M.-C. Scherrmann, S. Berteina-Raboin, European Journal of Organic Chemistry, 2014, 2014, 4643-4650
Stereoselective intermolecular [2 + 2]-photocycloaddition reactions of maleic anhydride: stereocontrolled and regiocontrolled access to 1,2,3-trifunctionalized cyclobutanes. F. Hernvann, G. Rasore, V. Declerck, D. J. Aitken, Org. Biomol. Chem., 2014, 12, 8212-8222
Practical Syntheses of Both Enantiomers of the Conformationally Restricted GABA Analogue cis-(2-Aminocyclobutyl)acetic Acid. H. Awada, S. Robin, R. Guillot, O. Yazbeck, D. Naoufal, N. Jaber, A. Hachem, D. J. Aitken, European Journal of Organic Chemistry, 2014, 2014, 7148-7155
2013
Reactivity of 1-aminoazetidine-2-carboxylic acid during peptide forming procedures: observation of an unusual variant of the hydrazino turn. A. Altmayer-Henzien, V. Declerck, R. Guillot, D. J. Aitken, Tetrahedron Letters, 2013, 54, 802-805
A unified synthesis of all stereoisomers of 2-(aminomethyl)cyclobutane-1-carboxylic acid. V. André, M. Gras, H. Awada, R. Guillot, S. Robin, D. J. Aitken, Tetrahedron, 2013, 69, 3571-3576
Molecular structures of the photodimers of 5-phenyluracil and 6-phenyluracil. A. Vidal, R. Paugam, R. Guillot, S. Faure, E. Pereira, D. J. Aitken, Tetrahedron Letters, 2013, 54, 2536-2537
Photochemical transformation of a 1,2-dihydropyridin-3-one: an original tandem retro-[4+2]/[2+2] cycloaddition process. D. J. Aitken, A. Frongia, X. Gaucher, J. Ollivier, H. Rafique, C. Sambiagio, F. Secci, Tetrahedron Letters, 2013, 54, 2825-2827
Total synthesis of high loading capacity PEG-based supports: evaluation and improvement of the process by use of ultrafiltration and PEG as a solvent. R. Turgis, I. Billault, S. Acherar, J. Auge, M.-C. Scherrmann, Green Chem., 2013, 15, 1016-1029
An unusual and diastereoselective rearrangement during an intramolecular ene reaction involving a disilane. A. Giros, R. Guillot, L. Blanco, S. Deloisy, Eur. J. Org. Chem., 2013, 5809-5813
Regioselective preparation of 7-oxanorborna-2,5-diene-2,3-dicarboxylic acid derivatives by the Diels-Alder reaction: a selective access to furans by retro-Diels-Alder reaction. N. Sultan, R. Guillot, L. Blanco, S. Deloisy, Synthesis, 2013, 45, 2018-2028
29Si-1H IMPACT HMBC: a suitable tool for analyzing silylated derivatives. J. Farjon, A. Giros, S. Deloisy, L. Blanco, J. Hannedouche, E. Schulz, D. Merlet, Magn. Reson. Chem., 2013, 51, 230-233
Solution State Conformational Preferences of Dipeptides Derived from N-Aminoazetidinecarboxylic Acid: An Assessment of the Hydrazino Turn. A. Altmayer-Henzien, V. Declerck, D. Merlet, J.-P. Baltaze, J. Farjon, R. Guillot, D. J. Aitken, Journal of Organic Chemistry, 2013, 78, 6031-6039
Fast-pulsing NMR techniques for the detection of weak interactions: successful natural abundance probe of hydrogen bonds in peptides. A. Altmayer-Henzien, V. Declerck, D. J. Aitken, E. Lescop, D. Merlet, J. Farjon, Organic & Biomolecular Chemistry, 2013, 11, 7611-7615
SENSASS NMR: New NMR techniques for enhancing the sensitivity and the spectral resolution of polymer supported chemicals. N. Prosa, M.-C. Scherrmann, D. Merlet, J. Farjon, Journal of Magnetic Resonance, 2013, 237, 63-72