Institut de Chimie Moléculaire et des Matériaux d'Orsay

Laboratoire de Synthèse Organique et Méthodologie - LSOM

Some of our activities

Photooxygenation

According to the IUPAC, the photooxygenation is the incorporation of molecular oxygen into a molecular entity. In this video you will see the photooxygenation of cyclopentadiene.
Can you guess the structure of the product?

Our research

Preparation of Imino Lactones by Electrophilic Cyclization of β,γ-Unsaturated Hydroxamates: Formation of 3-Cyanoprop-2-en-1-ones through Fragmentation Reactions

Houssam Trabulsi, Régis Guillot and Gérard Rousseau Eur. J. Org. Chem. 2010, 5884-5896 [PDF]

Reactions between hydroxamates and bromonium ion led not to N-alkoxy lactams but to the thermodynamically more stable imino lactones. If R1 = H and R2 =Ph, subsequent treatment with triethylamine led to (Z)-4-oxo-4-phenylbut-2-enenitrile through Beckman fragmentation.

 

Keywords

Aminoacids, Asymmetric synthesis, Heterocycles, Aminophosphonates, Enzymatic reactions, Quaternary centers, Cyclopeptides, Piperidines, Pyrrolidines, Photochemistry, [2+2] Cyloadditions, Kulinkvich reaction, Cyclopropanols, Natural products, Titanacyclopropanes, Palladium catalyzed reactions, Organosilicons compounds, Sila-chirality, Sila-diastereoselectivity, Diels-Alder Reaction, Radicalar reactions.