Institut de Chimie Moléculaire et des Matériaux d'Orsay

Laboratoire de Chimie des Procédés et des Substances Naturelles- LCPSN

Total synthesis of natural products

Cyrille Kouklovsky, Jean-Pierre Férézou, Guillaume Vincent, Valérie Alezra, Annie Pouilhès, Joël Dade, Pierre Sancibrao, Rodolphe Beauc, Morgan Jouanneau

We are currentely undergoing several total syntheses of natural products: We are especially interested in the synthesis of  polyketides and  alkaloids.   Synthetic strategies must give access to molecular diversity for the synthesis of analogues, and are based on new synthetic methodologies developped within our research group.  We are currently working on the synthesis of bafilomycin, leustroducsin, taurospongin and porantherdine.