Institut de Chimie Moléculaire et des Matériaux d'Orsay

Laboratoire de Chimie des Procédés et des Substances Naturelles- LCPSN


Research

Our research activity is devoted to modern organic synthesis and in particular the total synthesis of natural products.

This topic includes the development of new synthetic methods as well as the synthesis of biologically active natural products and analogues.  We are peculiarly interested in the preparation of chiral nitrogen-containing compounds using different methods for asymmetric synthesis. These methods are illustrated by the synthesis of natural products such as alkaloids or polyketides.  An important part of our recent work deals with the stereoselective synthesis of non-proteinogenic aminoacids.

Key words

Total synthesis, natural products, asymmetric cycloadditions, aminoacids, peptides, nitroso Diels-Alder, Blaise reaction, memory of chirality, methathesis, alkaloids, polyketides, indoles.