Laboratoire de Synthèse de Biomolécules- LSB

" Tin-Free Regioselective Radical De-O-benzylation by an Intramolecular Hydrogen Atom Transfer on Carbohydrate Templates " Attouche Angie, Urban Dominique, Beau Jean-Marie Angew. Chem. Int. Ed. 2013, 52, in press

" New Synthesis of A-Ring Aromatic Strigolactone Analogues and their Evaluation as Plant Hormones in Pea " Chen Victor X. , Boyer François-Didier, Rameau Catherine , Pillot Jean-Paul, Vors Jean-Pierre, Beau Jean-Marie Chem. Eur. J. 2013, 19, 4849-4857

" Novel imino sugar α-glucosidase inhibitors as antiviral compounds " Howe J.D., Smith N., Lee M.J-R., Ardes-Guisot N., vauzeilles Boris, Désiré J., Baron A., Blériot Y., Sollogoub M., Alonzi D.S., Butters T.D. Bioorg. Med. Chem. 2013, in press

" Light-induced tryptophan radical generation in a click modular assembly of sensitiser-tryptophan residue " Sheth Sujitraj, Baron Aurélie, Herrero Christian, vauzeilles Boris, Aukauloo Ally, Leibl Winfried Photochem. Photobiol. Sci. 2013, in press

" Click Chemistry as a Convenient Tool for the Incorporation of a Ruthenium Chromophore and a Nickel–Salen Monomer into a Visible-Light-Active Assembly " Herrero Christian, Batchelor Luke, Baron Aurélie, El Ghachtouli Sanae , Sheth Sujitraj, Guillot Régis, Vauzeilles Boris, Sircoglou Marie, Mallah Talal, Leibl Winfried, Aukauloo Ally Eur. J. Inorg. Chem. 2013, 494-499 [PDF]

" Highly Selective Formation of beta-Glycosides of N-Acetyl Glucosamine Using Catalytic Iron(III) Triflate " Stévenin Arnaud , Boyer François-Didier , Beau Jean-Marie Eur. J. Org. Chem. 2012, 699-1702

" Conformational study of glycal-type neuraminidase inhibitors " Surpateanu Georgiana , Soulé Jean-François , Beau Jean-Marie, Norsikian Stéphanie , Iorga Bogdan I. J. Carbohydr. Chem. 2012, 31, 114-129

" Remarkable stereoselectivity in intramolecular Borona-Mannich reactions: synthesis of conduramines " S. Norsikian, J-F. Soulé, A. Cannillo, Guillot Régis, M-E. Tran Huu Dau, Beau Jean-Marie Organic Letters 2012, 14, 544-547

" Vous prendrez bien un peu de sucre ? " Barroca-Aubry Nadine, Beau Jean-Marie, Bonnaffé David, Bourdreux Yann, Doisneau Gilles, Le Narvor Christine, Lepoittevin Bénédicte, Roger Philippe, Urban Dominique, Vauzeilles Boris Plein Sud 2011, Spécial Recherche 2010/2011, 104-115 [PDF]

" Lipo-Chitooligosaccharidic Nodulation Factors: Synthesis and Agricultural Perspectives " Beau Jean-Marie Chimia 2011, 65, 45-48

" NMR and Molecular Modelling Reveal Key Structural Features of Synthetic Nodulation Factors  " Morando Maria A., Nurisso Alessandra, Grenouillat Nathalie, Vauzeilles Boris, Beau Jean-Marie, Cañada F. Javier, Jiménez-Barbero Jesús, Imberty Anne Glycobiology 2011, 21, 824-833 [PDF]

" Design and synthesis by click triazole formation of paclitaxel mimics with simplified core and side-chain structures  " Le Manach Claire, Baron Aurélie, Guillot Régis, Vauzeilles Boris, Beau Jean-Marie Tetrahedron Letters 2011, 52, 1462-1465 [PDF]

" Iron(III) chloride-tandem catalysis for a one-pot regioselective protection of glycopyranosides " Bourdreux Yann, Lemétais Aurélie, Urban Dominique, Beau Jean-Marie Chem. Commun. 2011, 47, 2146-2148 [PDF]

" Stereochemistry, Total Synthesis, and Biological Evaluation of the New Plant Hormone Solanacol " Chen Victor X., Boyer François-Didier, Rameau Catherine, Retailleau Pascal, Vors Jean-Pierre, Beau Jean-Marie Chem. Eur. J. 2010, 16, 13941-13945

" Coupling the Petasis Condensation to an Iron(III) Chloride-Promoted Cascade Provides a Short Synthesis of Relenza Congeners " Soulé Jean-François, Mathieu Aurélie, Norsikian Stéphanie, Beau Jean-Marie Org. Lett. 2010, 12, 5322-5325

" Regio- and Stereocontrolled Allylic Substitution Catalyzed by Palladium on N-acetyl Neuraminic Acid Derivatives " Chang Chih-Wei, Norsikian Stéphanie, Guillot Régis, Beau Jean-Marie Eur. J. Org. Chem. 2010, 2280-2294

" Regioselective Control in the Oxidative Cleavage of 4,6-O-Benzylidene Acetals of Glycopyranosides by Dimethyldioxirane " Stévenin Arnaud, Boyer François-Didier, Beau Jean-Marie J. Org. Chem. 2010, 75, 1783-1786

" A mild and general method for preparation of a-glycosyl chlorides " Chang Chih-Wei, Chang Shih-Sheng, Chao Chin-Sheng, Mong Kwok-Kong T. Tetrahedron Letters 2009, 50, 4536-4540

" Useful Sialic Acid Modifications Catalyzed by Palladium " Chang Chih-Wei, Norsikian Stéphanie, Beau Jean-Marie Chem. Eur. J. 2009, 15, 5195-5199

" Fast Access to Robust C-Sialoside Multimers " Papin Caroline, Doisneau Gilles, Beau Jean-Marie Chemistry - A European Journal 2009, 15, 53-57

" Anomeric Samarium(III) Intermediates of N-Acetylneuraminic Acid from Anomeric 2-Pyridylsulfides " Adeline Malapelle, Zouleika Abdallah, Doisneau Gilles, Beau Jean-Marie Heterocycles 2009, 77, 1417-1424

" 2,6-Quinolinyl Derivatives as Potent VLA-4 Antagonists " Marie-Agnès Lassoie, Fabienne Broeders, Philippe Collart, Laurent Defrère, Françoise de Laveleye-Defais, Thierry Demaude, Abdoulaye Gassama, Gérald Guillaumet, Jean-Claude Hayez, Laszlo Kiss, Laurent Knerr, Jean-Marie Nicolas, Norsikian Stéphanie, Luc Quéré, Sylvain Routier, Valérie Verbois, Laurent Provins Bioorg. Med. Chem. Lett. 2007, 17, 142-146

"New and General Synthesis of β-C-Glycosyl Formaldehydes from Easily Available β-C-Glycosyl Propanones" Norsikian Stéphanie, Jennifer Zeitouni, Stéphanie Rat, Sylvie Gérard , Lubineau André Carbohydr. Res. 2007, 342, 2716-2728

"Tandem Catalysis for a One-Pot Regioselective Protection of Carbohydrates. The Example of Glucose" Antoine Français, Urban Dominique, Beau Jean-Marie Angew. Chem., Int. Ed. Engl 2007, 46, 8662-8665

"The solution conformation of C-glycosyl analogues of the sialyl Tn-antigen" García-Aparicio Víctor, Malapelle Adeline, Abdallah Zouleika, Doisneau Gilles, Santos I., Asensio Juan Luis, Cañada F. J., Beau Jean-Marie, Jiménes-Barbero Jesús Carbohydr. Res. 2007, 342, 1974-1982

"Expeditious Synthesis of C-Sialylated Compounds from the Anomeric Acetates of N-Acetylneuraminic acid." Malapelle Adeline, Coslovi Anna, Doisneau Gilles, Beau Jean-Marie Eur. J. Org. Chem. 2007, 3145-3157

"Lipid Analogs of the Nodulation Factors Using the Ugi/Passerini Multi Component Reactions: Preliminary Studies on the Carbohydrate Monomer" Grenouillat Nathalie, Vauzeilles Boris, Beau Jean-Marie Heterocycles 2007, 73, 891-901 [PDF]

"Two galactosyltransferases' selection of different binders from the same uridine-based dynamic combinatorial library" Valade A., Urban Dominique, Beau Jean-Marie J. Comb. Chem. 2007, 9, 1-4

"Direct Composition Analysis of a Dynamic Library of Imines in an Aqueous Medium" Zameo S., Vauzeilles Boris, Beau Jean-Marie Eur. J. Org. Chem. 2006, 5441-5444 [PDF]

"Anomeric Acetates of N-acetylneuraminic Acid are Useful C-sialyl Donors in Samarium-Mediated Reformatsky Coupling Reactions" Malapelle A., Abdallah Z., Doisneau Gilles, Beau Jean-Marie Angew. Chem., Int. Ed. Engl. 2006, 45, 6016-6020

"Target-Assisted Selection of Galactosyltransferase Binders from Dynamic Combinatorial Libraries. An Unexpected Solution with Restricted Amounts of the Enzyme" Valade A., Urban Dominique, Beau Jean-Marie ChemBioChem 2006, 1023-1027

"A Short Synthetic Route to b-C-glycosides of N-acetylglucosamine." Stéphanie Rat, Norsikian Stéphanie Synlett 2006, 7, 1004-1008

"Synthesis of C-glycosides and C-disaccharides using Mukaiyama aldol reaction in aqueous media." Jennifer Zeitouni, Norsikian Stéphanie, Merlet Denis, Lubineau André Advanced Synthesis & Catalysis 2006, 348, 1662-1670

"Dynamic Combinatorial Chemistry: Lysozyme Selects an Aromatic Motif that Mimics a Carbohydrate Residue" Zameo S. , Vauzeilles Boris, Beau Jean-Marie Angew. Chem., Int. Ed. Engl. 2005, 44, 965-969 [PDF]

"Highly enantioselective sequential Claisen-Ireland/Metathesis: Synthesis of cycloalkenes bearing two contiguous highly functionalised asymetric centers" Français Antoine, Bedel O., Picoul W., Meddour Abdelkrim, Courtieu Jacques, Haudrechy A. Tetrahedron : asymetry 2005, 16, 1141-55

"A new route to 2-C and 4-C-branched sugars by palladium-indium bromide-mediated carbonyl allylation." Norsikian Stéphanie, Lubineau André Org. Biomol. Chem. 2005, 3, 4089-4094

"Simple Synthesis of Nodulation Factor Analogs Exhibiting High Affinity Towards a Specific Binding Protein" Grenouillat N., Vauzeilles Boris, Bono J.-J., Samain E., Beau Jean-Marie Angew. Chem., Int. Ed. Engl. 2004, 43, 4644-4646 [PDF]

"Indium Promoted Barbier-type Allylations in Aqueous Media: A convenient approach to 4-C Branched Sugars and (1-4)-C-Disaccharides." Levoirier Eric, Canac Yves, Norsikian Stéphanie, Lubineau André Carbohydr. Res. 2004, 339, 2737-2747

"A convenient new route to protected and free 2,6-anhydro-D-glycero-D-gulo-heptoses (1-formyl-beta-D-glucopyranosides)." Zeitouni Jennifer, Norsikian Stéphanie, Lubineau André Tetrahedron Lett. 2004, 45, 7761-7763

"Synthesis of a carbon linked mimic of the disaccharidic component of the tumor-related sialylTn antigen" Abdallah Z., Doisneau Gilles, Beau Jean-Marie Angew. Chem., Int. Ed. Engl. 2003, 42, 5209-5212

"A highly selective route to b-C-glycosides via nonselective samarium iodide induced coupling reactions" Palmier S., Vauzeilles Boris, Beau Jean-Marie Org. Biomol. Chem. 2003, 1, 1097-1098 [PDF]

"A One Step b-Selective  Glycosylation of N-Acetyl Glucosamine and Recombinant Chitooligosaccharides" Vauzeilles Boris, Palmier S., Dausse B., Beau Jean-Marie Tetrahedron Lett. 2001, 42, 7567-7570 [PDF]

"Synthesis of 1,2-trans C-Glycosyl Compounds by Reductive Samariation of Anomeric Iodides." Miquel N., Doisneau Gilles, Beau Jean-Marie Chem. Commun. 2000, 2347-2348

"Reductive Samariation of Anomeric 2-Pyridyl Sulfones with Catalytic Nickel: An Unexpected Improvement in the Synthesis of 1,2-trans-Diequatorial C-Glycosyl compounds." N. Miquel, Doisneau Gilles, Beau Jean-Marie Angew. Chem. Int. Ed. Engl. 2000, 39, 4111-4114

"Conformational Differences Between C- and O-Glycosides: The a-C-Mannobiose/a-O-Mannobiose Case" Espinosa J.-F., Bruix M., Jarreton O., Skrydstrup T., Beau Jean-Marie, Jiménez-Barbero J. Chem. Eur. J. 1999, 5, 442-448

"Samarium Diiodide Promoted C-Glycosylation: An Application to the Stereospecific Synthesis of a-1,2-C-Mannobioside and Its Derivatives" Jarreton O., Skrydstrup T., Espinosa J.-F., Jiménez-Barbero J., Beau Jean-Marie Chem. Eur. J. 1999, 5, 430-441

"Radical Dimerization of Glycosyl 2-Pyridylsulfones with Samarium (II) Iodide in the Presence of HMPA" Doisneau Gilles, Beau Jean-Marie Tetrahedron Lett. 1998, 39, 3477-3480

"First Synthesis of a C-Glycoside Analogue of a Tumor Associated Carbohydrate Antigen Employing Samarium Diiodide Promoted C-Glycosylation" Urban Dominique, Skrydstrup T., Beau Jean-Marie Chem. Commun. 1998, 955-956

"Stereocontrolled Synthesis of a-C-Galactosamine Derivatives via Chelation Controlled C-Glycosylation" Urban Dominique, Skrydstrup T., Beau Jean-Marie J. Org. Chem. 1998, 63, 2507-2516

"A General Approach to 1,2-trans-C-glycosides via Glycosyl Samarium(III) Compounds" Skrydstrup T., Jarreton O., Mazéas D., Urban Dominique, Beau Jean-Marie Chem. Eur. J. 1998, 4, 655-671

"1,2-cis-C-Glycoside Synthesis by Samarium Diodide Promoted Radical Cyclizations" Skrydstrup T., Mazéas D., Elmouchir M., Doisneau Gilles, Riche C., Chiaroni A., Beau Jean-Marie Chem. Eur. J. 1997, 3, 1342-1355

"Further Studies in a-C-Mannosylation Promoted by Samarium Diiodide" Jarreton O., Skrydstrup T., Beau Jean-Marie Tetrahedron Lett. 1997, 38, 1767-1770

"Stereocontrolled Synthesis of a-C-galactosamine Derivatives Promoted by Samarium Diiodide : An Example of Chelation-controlled C-Glycosylation" Urban Dominique, Skrydstrup T., Riche C., Chiaroni A., Beau Jean-Marie J. Chem. Soc., Chem. Commun. 1996, 1883-1884

"The Stereospecific Synthesis of Methyl a-C-Mannobioside : A Potential Inhibitor of M. tuberculosis Binding to Human Macrophages" Jarreton O., Skrydstrup T., Beau Jean-Marie J. Chem. Soc., Chem. Commun. 1996, 1661-1662

"A Convenient Benzyloxymethylating Agent Induced by Samarium Diiodide" Skrydstrup T., Jespersen T., Beau Jean-Marie, Bols M. J. Chem. Soc., Chem. Commun. 1996, 515-516