Institut de Chimie Moléculaire et des Matériaux d'Orsay

Laboratoire de Catalyse Moléculaire - LCM


Equipe de Catalyse Moléculaire-ICMMO - Bât 420
Université Paris-Sud 11
15, rue Georges Clemenceau
91405 Orsay Cedex

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Giang Vo-Thanh obtained his Ms in 1994 and his Ph.D in 1997 from the University ‘Pierre et Marie Curie’ (Paris VI). After three year - postdoctoral fellowships in different universities, he took up, in 2001, an academic position as assistant professor at the University Paris-Sud 11. In 2006, he obtained his Habilitation diploma and in 2007, he was pointed Full Professor at the University Paris-Sud 11. His research interests include all aspects of synthetic methodology, including the design and synthesis of chiral ionic liquids and their uses as chiral reaction media (solvent and/or catalyst) in asymmetric synthesis and catalysis, the synthesis of new chiral ligands (amino alcohols, diamines, phosphines, NHC,…) derived from biomass products and their applications for asymmetric catalysis, and the preparation of molecules or molecular scaffolds of biological interest.


Tetrahedron Letters Most Cited Paper 2003-2006 Award’ in 2006: “First Application of Chiral Ionic Liquids in Asymmetric Baylis-Hillman Reaction” Tetrahedron Letters, 2004, 45, 6425-6428 .
Word Top-50 Most Cited Articles in 2004-2007 at ACS National Meeting in Boston, in July 2007.
Most accessed article in 2007: ‘Asymmetric Aza-Diels-Alder Reaction of Danishefsky's Diene with Imines in a Chiral Reaction Medium’ Beilstein Journal of Organic Chemistry, 2006, 2, 18.
The Institute of Industrial Chemistry Award for creative work in Green Chemistry in August 2009 in Hanoi, Viet Nam.


Bonus of Doctoral Supervision and Research (Prime d’Encadrement Doctoral et de Recherche) 2006-2010.
BQP (Bonus Qualité Pédagogique), 2008, University Paris-Sud.
BQR (Bonus Qualité Recherche) 2009, University Paris-Sud.

Visiting Professorships

University of Alabama, USA (6/2007), Institute of Polytechnic, Danang, Viet Nam (9/2008), North Bengal University, Darjeeling, India (4/2009), Institute of Industrial Chemistry, Hanoi, VietNam (7/2009), University of Sciences and Technology, Bratislava, Slovakia (11/2009), Dalian Institute of Chemical Physics, China (9/2010), Institute of Marine Biochemistry, Hanoi, VietNam (7/2011), East China Normal University in Shanghai, China (10/2011).

Invited lectures in international congress: 16
Invited lectures in national congress: 7
Invited lectures in international universities: 9
Oral presentation in congress: 18 (5 abroad)
Poster presentation in congress: 45 (16 abroad)
Publications (up to 2011): 42
Book Chapters: 2

Some representative publications

1.Efficient Enantiomeric Synthesis of Pyrrolidine and Piperidine Alkaloids From Tobacco.
François-Xavier Felpin, Sandrine Gérard, Giang Vo-Thanh, Richard J. Robins, Jean Villiéras and Jacques Lebreton. Journal of Organic Chemistry, 2001, 66, 6305-6312.

2.Microwave-Assisted Ruthenium-Catalyzed Olefin Metathesis Under Solvent-Free Conditions.
Giang Vo-Thanh* and André Loupy Tetrahedron Letters, 2003, 44, 9091-9094.

3.Solvent-Free Microwave-Assisted Preparation of Chiral Ionic Liquids from (-)-N-Methylepherine.
Giang Vo-Thanh,* Bruce Pégot and André Loupy. European Journal of Organic Chemistry, 2004, 5, 1112-1116.

4.Rh(I)-Catalyzed Solvent-Free Ortho-Alkylation of Aromatic Imines through MW Assistance.
Giang Vo-Thanh, Hind Lahrache, André Loupy, In-Jung Kim, Duck-Ho Chang, Chul-Ho Jun Tetrahedron, 2004, 60, 5539-5543.

5.First Application of Chiral Ionic Liquids as Reaction Media in Asymmetric Baylis-Hillman Reaction.
Bruce Pégot, Giang Vo-Thanh,* Didier Gori and André Loupy Tetrahedron Letters, 2004, 45, 6425-6428.

6.Ionic Liquids Promoted Aza Diels-Alder Reaction of Danishefsky’s Diene with Imines.
Bruce Pégot, Giang Vo-Thanh* Synlett, 2005, 9, 1409-1412.

7.An Efficient Microwave-Assisted Solvent-Free Synthesis of Pyrido-Fused Ring Systems Applying the tert-Amino Effect
Nadya Kaval, Beata Halasz-Dajka, Giang Vo-Thanh, Wim Dehaen, Péter Mátyus, André Loupy, and Erik Van der Eycken. Tetrahedron 2005, 61, 9053-9057.

8.Synthesis of Novel Chiral Imidazolium-based Ionic Liquids derived from Isosorbide and their Applications in Asymmetric aza Diels-Alder Reaction.
Olivier Nguyen Van Buu, Audrey Aupoix, Giang Vo-Thanh* Tetrahedron, 2009, 65, 2260-2265.

9.Solvent-Free Synthesis of Alkylthiazolium-based Ionic Liquids and their use as Catalysts in the Intramolecular Stetter Reaction Audrey Aupoix, Giang Vo-Thanh* Synlett, 2009, 12, 1915-1920.

10.Chiral ionic liquids derived from isosorbide: synthesis, properties and applications in asymmetric synthesis.
Olivier Nguyen Van Buu, Audrey Aupoix, Nhung Doan Thi Hong, Giang Vo-Thanh* New Journal of Chemistry, 2009, 33, 2060-2072.

11.Synthesis Of Imidazolium And Pyridinium-Based Ionic Liquids and Applications of 1-Alkyl-3-Methylimidazolium Salts as Pre-Catalysts for the Benzoin Condensation Using Solvent-Free Microwave Activation.
Audrey Aupoix, Bruce Pégot, Giang Vo-Thanh* Tetrahedron, 2010, 66, 1352-1356.

12.Synthesis of Functionalized Chiral Ammonium, Imidazolium and Pyridinium-based Ionic Liquids derived from (-)-Ephedrine using solvent-free microwave activation. Applications for the Asymmetric Michael Addition Thi Kim Thu Truong, Giang Vo-Thanh* Tetrahedron, 2010, 66, 5277-5282.

13.New class of chiral ligands derived from isosorbide: first application in asymmetric transfer hydrogenation.
Duy Huynh-Khanh, Houssein Ibrahim, Martial Toffano, Giang Vo-Thanh*
Tetrahedron: Asymmetry, 2010, 21, 1542-1548.

14.Asymmetric transfer hydrogenation of aromatic ketone using rhodium complexes of chiral N-heterocyclic carbenes derived from (S)-pyroglutamic acid.
Audrey Aupoix, Chloée Bournaud, Giang Vo-Thanh* European Journal of Organic Chemistry, 2011, 2772-2776.

15. Efficient copper-induced coupling between NH-fluoroalkylated sulfoximines and aryl iodides or bromides.
Yohan Macé, Bruce Pégot, Régis Guillot, Chloée Bournaud, Martial Toffano, Giang Vo-Thanh*, Emmanuel Magnier* Tetrahedron, 2011, 67, 7575-7580.

16.Synthesis of a new class of ligands derived from isosorbide and their application to asymmetric reduction of aromatic ketones by transfer hydrogenation.
Duy Huynh-Khanh, Houssein Ibrahim, Emilie Kolodziej, Martial Toffano, Giang. Vo-Thanh*
New Journal of Chemistry, 2011, 35, 2622-2631.

International Collaborations

University of Seoul, South Korea (Prof. H. Jun), University of Science and Technology, Slovakia (Profs. V. Milata and T. Gracza), University of Leuven, Belgium (Prof. Dr. E. Van der Eycken), Institute of Organic and Pharmaceutical Chemistry National Hellenic Research Foundation, Greece (Prof. G. Heropoulos), University National of Science, Viet Nam (Prof. Le Ngoc Thach). Institute of Marine Biochemistry of Hanoi, Vietnam (Dr. Doan Thi Mai Huong), Torino University, Italy (Prof. G. Cravotto), University of Osaka, Japan (Prof. H. Sasai), East China Nornal University in Shanghai, China (Prof. Y. Liu).

Industrial Collaborations

Interchim, Merck, CEM, Sanofi companies

Project Coordinators

COST D32/0006/004 (2005-2010), Stefanik (2008-2010). PRES UniverSud (2010-2011), Lotus (2011-2013). Cai Yuanpei (2011-2013).