Institut de Chimie Moléculaire et des Matériaux d'Orsay

Laboratoire de Chimie Bioorganique et Bioinorganique - LCBB

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Theme 3 (H. Korri-Youssoufi)
Design of electrochemical biosensors and biochips
for diagnosis and analysis

H. Dorizon, H. Korri-Youssoufi


Carbon nanotubes


  • Carbon nanotubes are studied as transducers due to their electronic properties and high surface. The methods of functionalization as well as the various functionalization modes have been developed:


Covalent attachment

Interaction through π- π stacking

chemical modification

Chemical modification


Association with conducting polymers

electro modification

Electrochemical modification

CN porphyrin

Association with metalloporphyrins


  • Carbon nanotubes and their association with other materials has been studied for various biosensors systems:


NTA copper

Modification with NTA/copper for his-Tag antibody immobilization and protein detection through redox
signal of copper

PP dendrimers

Association with conducting polypyrrole and redox dendrimers through π-π stacking interaction for DNA sensors development


CN dendrimers

Association with redox dendrimers through
chemical modification for aptasensors development

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