Institut de Chimie Moléculaire et des Matériaux d'Orsay

Laboratoire de Chimie Bioorganique et Bioinorganique - LCBB

Stéphanie Pethe

Maître de Conférences 

UMR 8182, ICMMO
Institut de Chimie Moléculaire et des Matériaux d’Orsay
Université Paris-Sud, Bât 420
91405 Orsay Cedex

Tel : 01 69 15 47 20
Fax : 01 69 15 72 81

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Domaines de recherche :
Thème 2

Enseignements :

Publications (2006-2017) :


Polyamine-based analogs and conjugates as antikinetoplastid agents.
Elodie JAGU, Sébastien POMAREL, Stéphanie PETHE, Philippe M. LOISEAU, Raphaël LABRUERE
Eur. J. Med. Chem. 2017, in press.

Synthesis and in vitro antikinetoplastid activity of polyamine-hydroxybenzotriazole conjugates.
Elodie JAGU, Sébastien POMEL, Alba DIEZ-MARTINEZ, Florence RAMIANDRASOA , R. Luise KRAUTH-SIEGEL, Stéphanie PETHE, Casimir BLONSKI, Raphaël LABRUERE, Philippe M. LOISEAU
Bioorg. Med. Chem. 2017, 25, 84-90.


Design, synthesis and in vitro antikinetoplastid evaluation of N-acylated putrescine, spermidine and spermine derivatives.
Elodie JAGU, Rachid DJILLALI, Sébastien POMEL, Florence RAMIANDRASOA, Stéphanie PETHE, Raphaël LABRUERE, Philippe M. LOISEAU, Casimir BLONSKI
Bioorg. Med. Chem. Lett. 2015, 25, 207-209.

Synthesis and Biological Evaluation of Acridine Derivatives as Antimalarial Agents.
Xiao-Min YU, Florence RAMIANDRASOA, Lucie GUETZOYAN, Bruno PRADINES, Edgar QUINTINO, Danièle GADELLE, Patrick FORTERRE, Thierry CRESTEIL, Jean-Pierre MAHY, and Stéphanie PETHE
ChemMedChem 2012, 7, 587-605.

Coordination chemistry studies and peroxidase activity of a new artificial metalloenzyme built by the “Trojan horse” strategy.
Q. RAFFY, R. RICOUX, E. SANSIAUME, S. PETHE, and J.-P. MAHY
J. Mol. Catal. A: Chem. 2010, 317, 19-26.

Antimalarial acridines: Synthesis, in vitro activity against P. falciparum and interaction with hematin.
L. GUETZOYAN, X.-M. YU, F. RAMIANDRASOA, S. PETHE, C. ROGIER, B. PRADINES, T. CRESTEIL, M. PERREE-FAUVET, and J.-P. MAHY
Bioorg. Med. Chem. 2009, 17, 8032-8039.

Flavocytochrome b2 : reactivity of its flavin with molecular oxygen.
A. K. OULD BOUBACAR, S. PETHE, J.-P. MAHY, and F. LEDERER
Biochemistry 2007, 46, 13080-13088.

Molecular tongs containing amino acid mimetic fragments: new inhibitors of wild-type and mutated
HIV-1 protease dimerization.
L. BANNWARTH, A. KESSLER, S. PETHE, B. COLLINET, N. MERABET, N. BOGGETTO, S. SICSIC, M. REBOUD-RAVAUX, and S. ONGERI
J. Med. Chem. 2006, 49, 4657-4664.


Accueil LCBB